CJC-1295 (NO DAC)/Ipamorelin Blend
Growth Hormone Secretagogue Blend
CAS: 863288-34-0, 170851-70-4
CJC-1295 (NO DAC)/Ipamorelin is a research-grade blend combining a growth hormone-releasing hormone (GHRH) analog with a selective ghrelin receptor agonist. By simultaneously activating both GHRH and ghrelin signaling pathways, this combination produces a synergistic amplification of pulsatile growth hormone (GH) release that exceeds either compound administered alone. CJC-1295 (NO DAC), a 30-amino acid modified GHRH analog, extends the GH release window while Ipamorelin (MW 711.85 g/mol) provides selective, dose-dependent GH secretion without significantly elevating cortisol or prolactin. This dual-pathway approach has made the blend a preferred tool in GH axis research.
Key Research Findings:
- In preclinical models, the combination produced 2-3x greater GH pulse amplitude compared to either peptide administered individually
- Rodent studies showed sustained IGF-1 elevation over 6-12 hours post-administration without desensitization of the GH axis
- In vitro pituitary cell assays demonstrated additive receptor activation across GHRH-R and GHS-R1a pathways
- Preclinical pharmacokinetic data indicated complementary half-life profiles, extending the effective GH secretion window
For laboratory and research use only.
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Technical Details & Purity Analysis
Documented Studies & Applications
This peptide is intended for laboratory research purposes only. Below are documented research applications.
Storage & Reconstitution
Storage Conditions
Store lyophilized peptide at -20°C for long-term storage (up to 24 months). For short-term storage (up to 4 weeks), 4°C is acceptable. Keep away from light and moisture.
Reconstitution
Reconstitute with bacteriostatic water or sterile water. Add solvent slowly down the side of the vial. Do not shake vigorously. Store reconstituted peptide at 4°C.
Handling Precautions
Handle with appropriate laboratory safety equipment. This product is for research use only and not for human consumption.