Tesamorelin (GHRH Analog)
Growth Hormone Releasing Factor • 44 Amino Acids
CAS: 218949-48-5
Tesamorelin is a 44-amino acid synthetic analog of growth hormone-releasing hormone (GHRH) featuring a trans-3-hexenoic acid modification at the N-terminus that enhances proteolytic stability. It is the only GHRH analog to have received FDA approval (indicated for HIV-associated lipodystrophy), providing a uniquely well-characterized pharmacological profile for GH axis research. Tesamorelin selectively stimulates GH secretion from the anterior pituitary without affecting cortisol, prolactin, or thyroid hormone levels.
Key Research Findings:
- Clinical and preclinical studies documented approximately 20% reduction in visceral adipose tissue (VAT) following 26-week protocols
- GH stimulation testing showed 4-6 fold increases in peak GH levels without altering cortisol or prolactin secretion
- Body composition studies demonstrated selective VAT reduction with preservation of subcutaneous fat and lean mass
- IGF-1 levels increased by 40-60% from baseline with sustained elevation over treatment periods
For laboratory and research use only.
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Technical Details & Purity Analysis
Documented Studies & Applications
This peptide is intended for laboratory research purposes only. Below are documented research applications.
Storage & Reconstitution
Storage Conditions
Store lyophilized peptide at -20°C for long-term storage (up to 24 months). For short-term storage (up to 4 weeks), 4°C is acceptable. Keep away from light and moisture.
Reconstitution
Reconstitute with bacteriostatic water or sterile water. Add solvent slowly down the side of the vial. Do not shake vigorously. Store reconstituted peptide at 4°C.
Handling Precautions
Handle with appropriate laboratory safety equipment. This product is for research use only and not for human consumption.
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